Intermittent fasting is known to improve mitochondrial function, which plays a significant role in cellular energy production and overall health. When you fast, the body adapts by enhancing mitochondrial efficiency and promoting the repair of damaged mitochondria. This process, known as mitochondrial biogenesis, can increase energy production and improve cellular function.
Research suggests intermittent fasting can benefit mitochondrial networks by promoting a balance between fused and fragmented states. This balance, or plasticity, is associated with a longer lifespan and reduced age-related diseases. These benefits are achieved through dietary restriction or fasting, improving mitochondrial coordination with other cellular structures, such as peroxisomes, which are involved in fat metabolism (The Institute for Functional Medicine) (New Atlas).
Additionally, intermittent fasting has been found to positively affect brain health. It can increase the survival and formation of neurons in specific brain regions, potentially supporting memory, learning, and emotional health. However, it's worth noting that the evidence in humans is mixed, with some studies showing improved cognitive function. In contrast, others show no significant effect (Harvard Gazette) (medicalxpress).
Various supplements can also support mitochondrial function. Coenzyme Q10 (CoQ10) is a critical component in the mitochondrial respiratory chain, facilitating electron transfer and supporting energy production. Alpha-lipoic acid (ALA) is another supplement that helps reduce oxidative stress and supports mitochondrial health. Berberine and bitter melon are plant-based supplements that are believed to promote mitochondrial function and energy production (SelfDecode Health) (Kim Crawford, M.D.).
Intermittent fasting and other calorie-restriction approaches can offer significant benefits for mitochondrial health. However, to ensure safety and address individual health concerns, it's important to consult with healthcare professionals before starting any fasting regimen or supplement routine.
